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What are the differences between Botox, Dysport and Nuceiva?

Updated: Dec 12, 2023

Botox, Dysport, and Nuceiva are all brands of botulinum toxin type A, which is a neurotoxin that is used to temporarily paralyze muscles. They are all approved in Canada for the treatment of facial wrinkles and lines, but there are some differences between the three products that patients should be aware of when considering treatment.


Botox is the most well-known and widely used brand of botulinum toxin type A. It has been used for cosmetic purposes for over 20 years and is considered the gold standard in wrinkle reduction. Botox is made by the pharmaceutical company Allergan and contains the active ingredient onabotulinumtoxinA. It is typically used to treat lines and wrinkles in the forehead, between the eyebrows, and around the eyes.


difference between Botox, Dysport and Nuceiva

Dysport is another brand of botulinum toxin type A that is used for cosmetic purposes. It is made by the pharmaceutical company Ipsen and contains the active ingredient abobotulinumtoxinA. Dysport is similar to Botox in its mechanism of action and can be used to treat lines and wrinkles in the same areas as Botox. Some patients report that Dysport may have a faster onset of action and may spread to a wider area than Botox, which can make it more effective for certain types of wrinkles.


Nuceiva is the newest brand of botulinum toxin type A to receive Canadian approval for cosmetic use. It is made by the pharmaceutical company Evolus and contains the active ingredient prabotulinumtoxinA-xvfs. Nuceiva is marketed as a "next-generation" neurotoxin and is said to have a more pure and precise formulation than Botox or Dysport. It is also reported to have a faster onset of action and may last longer than other botulinum toxin type A products.


When it comes to dosing and administration, there are some differences between Botox, Dysport, and Nuceiva. While the three products are all made from botulinum toxin type A, they are not interchangeable, and each one requires a specific dose and injection technique. For example, the dosing for Dysport is typically higher than the dosing for Botox, and Nuceiva is generally considered to be more potent than both Botox and Dysport.


One potential advantage of Nuceiva over other botulinum toxin type A products is that it may be less likely to cause antibody formation, which can reduce the effectiveness of the treatment over time. Antibody formation can occur when the body recognizes the botulinum toxin as a foreign substance and produces antibodies to fight it. This can cause the treatment to become less effective or stop working altogether. While antibody formation is rare, it can happen with repeated use of botulinum toxin type A.


Another potential advantage of Nuceiva is that it may have a lower risk of side effects than other botulinum toxin type A products. While all three products have a similar risk of side effects, such as bruising, swelling, and muscle weakness, some patients may experience fewer side effects with Nuceiva.


Ultimately, the choice between Botox, Dysport, and Nuceiva will depend on the individual patient's needs and preferences. Some patients may prefer the tried-and-true formula of Botox, while others may prefer the faster onset of action of Dysport or the purported purity and potency of Nuceiva. Patients should consult with a qualified and experienced provider such as thepurGlow Medical Spa and clinic to determine which product is best for them and to ensure that the treatment is performed safely and effectively.

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